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John Wayne Casserole Recipe

John Wayne Casserole Recipe

5 Stars 4 Stars 3 Stars 2 Stars 1 Star 4.8 from 138 reviews
  • Author: Paula
  • Prep Time: 30 minutes
  • Cook Time: 40 minutes
  • Total Time: 1 hour 10 minutes
  • Yield: 6 servings
  • Category: Casserole
  • Method: Baking
  • Cuisine: American

Description

John Wayne Casserole is a hearty and flavorful baked dish that combines seasoned ground beef, a cheesy biscuit layer, and a creamy cheese topping. Perfect for a comforting family meal, this casserole features a savory beef filling topped with a rich cheese blend and a tender biscuit crust, baked to perfection for a satisfying dinner.


Ingredients

Units Scale

Meat and Vegetables

  • 1 lb lean ground beef
  • 1 cup diced yellow onion
  • 20 oz Rotel diced tomatoes and green chilies, drained
  • 12 oz canned corn, drained
  • 1 cup water
  • 1 oz taco seasoning

Biscuit Layer

  • 3 cups Bisquick mix
  • 1 cup water

Topping

  • 7.5 oz Philadelphia whipped chive cream cheese
  • 1/2 cup mayonnaise
  • 1 tbsp garlic powder
  • 1/2 tsp salt
  • 2 cups shredded mozzarella and cheddar cheese blend

Instructions

  1. Preheat oven: Preheat your oven to 325°F (160°C) to ensure it’s ready for baking.
  2. Cook ground beef: In a large skillet, add the lean ground beef over medium-high heat. Crumble the beef with a spatula as it cooks, until fully browned and cooked through, about 8-10 minutes. Drain excess grease and transfer to a plate.
  3. Prepare beef mixture: Return the skillet to the heat, add 1 cup water and taco seasoning, stirring well. Let simmer over medium-high heat for 4 minutes to develop flavor.
  4. Add vegetables: Stir in the diced onions, drained Rotel tomatoes, and drained corn. Reduce heat to low and simmer until heated through, about 5 minutes.
  5. Make biscuit dough: In a mixing bowl, combine Bisquick mix and 1 cup water. Stir until a sticky dough forms.
  6. Assemble the crust: Grease a 9×13-inch baking dish. Spread the biscuit dough evenly on the bottom of the dish to form a crust.
  7. Layer beef mixture: Evenly spread the cooked beef mixture over the biscuit crust in the baking dish.
  8. Prepare cheese topping: In a separate bowl, beat the cream cheese, mayonnaise, garlic powder, and salt together with an electric mixer until smooth and creamy.
  9. Add topping: Spread the cream cheese mixture evenly over the beef layer.
  10. Add cheese: Sprinkle the shredded mozzarella and cheddar cheese blend evenly over the top.
  11. Bake: Place the assembled casserole in the preheated oven and bake for 40 minutes, or until the cheese is melted and bubbly, and the top is golden brown.
  12. Serve: Remove from oven and let sit for 5 minutes before slicing and serving to allow the layers to set.

Notes

  • For a spicier version, add diced jalapeños to the beef mixture.
  • You can substitute ground turkey or chicken for a leaner option.
  • Make ahead: assemble the casserole and refrigerate for up to 24 hours before baking.
  • Leftovers can be stored in an airtight container for up to 3 days and reheated in the microwave.
  • Replace mayonnaise with sour cream for a slightly tangier topping.

Nutrition

  • Serving Size: 1 slice
  • Calories: 560 kcal
  • Sugar: 4 g
  • Sodium: 950 mg
  • Fat: 30 g
  • Saturated Fat: 12 g
  • Unsaturated Fat: 15 g
  • Trans Fat: 0.5 g
  • Carbohydrates: 45 g
  • Fiber: 4 g
  • Protein: 30 g
  • Cholesterol: 120 mg